2019 US Pharma

Financial Strength Rankings using Artificial Intelligence

Top rated	90 of 363
Best rating	394 %
Worst rating	-4,724 %
New companies	61
Negative Economic Capital Ratio	106 of 363

Ampio Pharmaceuticals Inc. climbed 320 positions from 322 to 2 due to its excellent Net Income.ARTELO BIOSCIENCES INC. lost 326 positions from 33 to 359 due to its bad Assets, Current.MARIZYME INC. entered the 2019 ranking at rank 7, making it the best newcomer.

Revenues	414 B
Assets	1.02 K
Expenses	378 B
Stockholders Equity	508 B
Unprofitable Companies	315 of 363

Rank	Company	Seal	Rating Value	Trend
1	SIGA TECHNOLOGIES INC		394.00%	304.0
2	Ampio Pharmaceuticals Inc.		376.73%	320.0
3	IVERIC bio Inc.		367.49%	152.0
4	BIOSPECIFICS TECHNOLOGIES CORP		366.30%	0.0
5	SPRING PHARMACEUTICAL GROUP INC.		359.53%	1.0
6	ENANTA PHARMACEUTICALS INC		344.52%	3.0
7	MARIZYME INC.		341.24%	0.0
8	XYNOMIC PHARMACEUTICALS HOLDINGS INC.		336.62%	-3.0
9	Viking Therapeutics Inc.		319.26%	225.0
10	MADRIGAL PHARMACEUTICALS INC.		318.89%	0.0
11	CORCEPT THERAPEUTICS INC		316.50%	-8.0
12	Jazz Pharmaceuticals plc		316.25%	-5.0
13	ARENA PHARMACEUTICALS INC		307.08%	72.0
14	ANAPTYSBIO INC		292.51%	-4.0
15	GERON CORP		289.05%	9.0
16	Equillium Inc.		283.73%	0.0
17	CV Sciences Inc.		282.92%	95.0
18	ARATANA THERAPEUTICS INC.		282.83%	153.0
19	NEKTAR THERAPEUTICS		281.36%	219.0
20	Principia Biopharma Inc.		280.59%	0.0
21	G1 Therapeutics Inc.		277.22%	77.0
22	MEDICINOVA INC		273.11%	13.0
23	GLYCOMIMETICS INC		272.17%	4.0
24	UNITED THERAPEUTICS Corp		271.62%	18.0
25	TENAX THERAPEUTICS INC.		271.61%	-12.0
26	GYRE THERAPEUTICS INC.		271.37%	119.0
27	ABEONA THERAPEUTICS INC.		270.58%	-15.0
28	Catalent Inc.		269.34%	-7.0
29	EAGLE PHARMACEUTICALS INC.		268.81%	-12.0
30	ACHILLION PHARMACEUTICALS INC		267.42%	-12.0
31	ABBOTT LABORATORIES		267.27%	-15.0
32	CASSAVA SCIENCES INC		263.47%	147.0
33	Xencor Inc		261.89%	59.0
34	Aadi Bioscience Inc.		260.16%	0.0
35	MyoKardia Inc.		256.68%	3.0
36	Vanda Pharmaceuticals Inc.		256.64%	83.0
37	RENOVARO BIOSCIENCES INC.		254.63%	204.0
38	ZOGENIX INC.		252.10%	-12.0
39	Ra Pharmaceuticals Inc.		251.86%	97.0
40	Aptinyx Inc.		251.41%	0.0
41	Carisma Therapeutics Inc.		250.99%	-7.0
42	Y-mAbs Therapeutics Inc.		243.10%	0.0
43	PROCYON CORP		241.29%	-14.0
44	Provention Bio Inc.		240.17%	0.0
45	DiaMedica Therapeutics Inc.		239.65%	0.0
46	REGENERON PHARMACEUTICALS INC.		237.96%	8.0
47	Edesa Biotech Inc.		234.23%	26.0
48	LUMOS PHARMA INC.		234.19%	0.0
49	INFINITY PHARMACEUTICALS INC.		232.40%	108.0
50	CHIMERIX INC		232.00%	-22.0
51	VYNE Therapeutics Inc.		231.18%	69.0
52	Entasis Therapeutics Holdings Inc.		229.14%	0.0
53	Corvus Pharmaceuticals Inc.		226.50%	44.0
54	Neoleukin Therapeutics Inc.		226.36%	12.0
55	Arcus Biosciences Inc.		225.13%	0.0
56	Arbutus Biopharma Corp		224.87%	59.0
57	Monopar Therapeutics		224.70%	188.0
58	NANOVIRICIDES INC.		224.61%	66.0
59	Spero Therapeutics Inc.		221.72%	-7.0
60	LIXTE BIOTECHNOLOGY HOLDINGS INC.		218.28%	195.0
61	CymaBay Therapeutics Inc.		217.22%	9.0
62	AgeX Therapeutics Inc.		216.50%	0.0
63	Endo International plc		215.72%	-6.0
64	CONCERT PHARMACEUTICALS INC.		214.05%	-62.0
65	Neurotrope Inc.		213.31%	64.0
66	Sage Therapeutics Inc.		213.19%	0.0
67	Kura Oncology Inc.		212.40%	13.0
68	SYNLOGIC INC.		210.73%	11.0
69	Merck & Co. Inc.		209.78%	-32.0
70	FIVE PRIME THERAPEUTICS INC.		209.44%	14.0
71	Tempest Therapeutics Inc.		207.51%	52.0
72	Kiniksa Pharmaceuticals Ltd.		206.83%	0.0
73	Citius Pharmaceuticals Inc.		206.76%	-12.0
74	Calithera Biosciences Inc.		205.87%	-7.0
75	AbbVie Inc.		204.32%	-35.0
76	CHEMBIO DIAGNOSTICS INC.		203.84%	0.0
77	Xenon Pharmaceuticals Inc.		202.27%	83.0
78	Strongbridge Biopharma plc		198.70%	213.0
79	Unity Biotechnology Inc.		197.96%	0.0
80	BioXcel Therapeutics Inc.		197.55%	0.0
81	Intra-Cellular Therapies Inc.		197.33%	-67.0
82	Evelo Biosciences Inc.		195.42%	0.0
83	Mirati Therapeutics Inc.		194.49%	-27.0
84	ACADIA PHARMACEUTICALS INC		192.52%	57.0
85	VERTEX PHARMACEUTICALS INC MA		190.59%	41.0
86	Theriva Biologics Inc.		189.68%	163.0
87	Cocrystal Pharma Inc.		187.94%	-64.0
88	OPKO HEALTH INC.		187.61%	-5.0
89	Phio Pharmaceuticals Corp.		187.44%	230.0
90	Amphastar Pharmaceuticals Inc.		186.96%	-32.0
91	IMMUNE DESIGN CORP.		186.80%	-48.0
92	Protagonist Therapeutics Inc		183.73%	13.0
93	ALIMERA SCIENCES INC		183.35%	-15.0
94	OncoMed Pharmaceuticals Inc		182.36%	189.0
95	Epizyme Inc.		182.01%	-35.0
96	RELIV INTERNATIONAL INC		180.18%	0.0
97	Alaunos Therapeutics Inc.		179.94%	0.0
98	ARQULE INC		179.04%	48.0
99	Zymeworks BC Inc.		177.71%	0.0
100	Theravance Biopharma Inc.		175.73%	28.0
101	Homology Medicines Inc.		171.70%	0.0
102	BIOMARIN PHARMACEUTICAL INC		171.31%	25.0
103	ARROWHEAD PHARMACEUTICALS INC.		170.87%	4.0
104	KINETA INC. DE		170.74%	65.0
105	BeiGene Ltd.		170.68%	12.0
106	ALEXION PHARMACEUTICALS INC.		169.58%	-7.0
107	BODY & MIND INC.		169.10%	0.0
108	ROCKET PHARMACEUTICALS INC.		167.97%	85.0
109	ASSEMBLY BIOSCIENCES INC.		166.91%	0.0
110	HERON THERAPEUTICS INC. DE		165.21%	125.0
111	LIFECORE BIOMEDICAL INC. \DE\		165.09%	-5.0
112	DURECT CORP		164.75%	-21.0
113	Aeglea BioTherapeutics Inc.		162.78%	-42.0
114	AGIOS PHARMACEUTICALS INC.		162.46%	69.0
115	ALNYLAM PHARMACEUTICALS INC.		160.04%	-79.0
116	Molecular Templates Inc.		159.71%	-67.0
117	Aimmune Therapeutics Inc.		159.64%	4.0
118	NightHawk Biosciences Inc.		158.68%	138.0
119	Astria Therapeutics Inc.		157.76%	158.0
120	NATURES SUNSHINE PRODUCTS INC		156.62%	13.0
121	HARROW INC.		154.27%	145.0
122	Allergan plc		154.11%	-4.0
123	Zynerba Pharmaceuticals Inc.		153.57%	-48.0
124	CATALYST PHARMACEUTICALS INC.		152.13%	-105.0
125	Cryoport Inc.		151.94%	-63.0
126	GW PHARMACEUTICALS PLC		147.93%	0.0
127	ARVINAS INC.		147.76%	0.0
128	SPECTRUM PHARMACEUTICALS INC		146.82%	-27.0
129	Blueprint Medicines Corp		146.42%	-107.0
130	Orgenesis Inc.		146.03%	68.0
131	RIGEL PHARMACEUTICALS INC		143.86%	0.0
132	Altimmune Inc.		142.82%	35.0
133	Elanco Animal Health Inc		141.80%	0.0
134	Aclaris Therapeutics Inc.		141.29%	-102.0
135	Akebia Therapeutics Inc.		140.04%	82.0
136	Intec Pharma Ltd.		139.78%	0.0
137	Syros Pharmaceuticals Inc.		139.02%	6.0
138	NEUROPATHIX INC.		136.60%	190.0
139	UroGen Pharma Ltd.		135.54%	0.0
140	CAMBREX CORP		134.72%	-99.0
141	ALBIREO PHARMA INC.		134.09%	-96.0
142	OTONOMY INC.		133.31%	-29.0
143	CHINA PHARMA HOLDINGS INC.		132.54%	-11.0
144	Larimar Therapeutics Inc.		131.87%	5.0
145	MUSTANG BIO INC.		130.07%	-99.0
146	Pfenex Inc.		129.29%	-21.0
147	ORAMED PHARMACEUTICALS INC.		128.56%	34.0
148	Savara Inc		126.55%	-59.0
149	Sarepta Therapeutics Inc.		125.56%	-18.0
150	Cogent Biosciences Inc.		123.76%	0.0
151	ALPINE IMMUNE SCIENCES INC.		123.50%	-136.0
152	Apellis Pharmaceuticals Inc.		121.34%	-78.0
153	AGILE THERAPEUTICS INC		121.25%	10.0
154	uniQure N.V.		121.12%	61.0
155	PERRIGO Co plc		120.21%	-8.0
156	PROTHENA CORP PUBLIC LTD CO		118.56%	-79.0
157	SUPERNUS PHARMACEUTICALS INC.		118.33%	-71.0
158	DMK PHARMACEUTICALS Corp		117.97%	-18.0
159	MACROGENICS INC		116.90%	-115.0
160	Avid Bioservices Inc.		116.40%	27.0
161	VBI Vaccines Inc BC		115.86%	-98.0
162	Matinas BioPharma Holdings Inc.		115.23%	62.0
163	Cellectar Biosciences Inc.		113.61%	32.0
164	LIGAND PHARMACEUTICALS INC		112.99%	-50.0
165	Minerva Neurosciences Inc.		111.79%	-61.0
166	ATHERSYS INC NEW		111.74%	104.0
167	NEXIEN BIOPHARMA INC.		110.57%	0.0
168	AKCEA THERAPEUTICS INC.		110.27%	-10.0
169	IONIS PHARMACEUTICALS INC		110.22%	28.0
170	SCYNEXIS INC		109.80%	51.0
171	Lifevantage Corp		108.45%	19.0
172	CohBar Inc.		108.04%	24.0
173	ANI PHARMACEUTICALS INC		106.82%	1.0
174	Pacira BioSciences Inc.		104.42%	0.0
175	BRISTOL MYERS SQUIBB CO		104.41%	7.0
176	CUMBERLAND PHARMACEUTICALS INC		104.28%	-74.0
177	Sonoma Pharmaceuticals Inc.		104.24%	-169.0
178	Xenetic Biosciences Inc.		102.90%	-85.0
179	MERRIMACK PHARMACEUTICALS INC		102.58%	-178.0
180	Moleculin Biotech Inc.		101.93%	-98.0
181	EYENOVIA INC.		101.68%	-27.0
182	Eterna Therapeutics Inc.		101.41%	17.0
183	Histogen Inc.		101.32%	-44.0
184	Tonix Pharmaceuticals Holding Corp.		100.77%	-62.0
185	Kadmon Holdings Inc.		97.37%	0.0
186	JOHNSON & JOHNSON		95.20%	-10.0
187	PFIZER INC		93.97%	-25.0
188	CTI BIOPHARMA CORP		93.96%	76.0
189	RVL Pharmaceuticals plc		92.01%	0.0
190	Statera Biopharma Inc.		91.99%	24.0
191	AYTU BIOPHARMA INC		89.92%	99.0
192	PROGENICS PHARMACEUTICALS INC		89.24%	21.0
193	ARDELYX INC.		86.03%	-128.0
194	Dicerna Pharmaceuticals Inc		83.04%	-84.0
195	LANNETT CO INC		82.98%	-6.0
196	Travere Therapeutics Inc.		80.81%	-44.0
197	Dova Pharmaceuticals Inc.		79.81%	-41.0
198	VERU INC.		79.41%	-167.0
199	PLx Pharma Winddown Corp.		79.00%	66.0
200	Mylan II B.V.		77.83%	0.0
201	Evolus Inc.		75.80%	0.0
202	EXICURE INC.		74.53%	-43.0
203	Iterum Therapeutics plc		74.34%	0.0
204	Revance Therapeutics Inc.		70.27%	-156.0
205	Aravive Inc.		67.78%	-44.0
206	KalVista Pharmaceuticals Inc.		66.66%	-125.0
207	Imunon Inc.		65.94%	-21.0
208	Verastem Inc.		65.75%	3.0
209	PHIBRO ANIMAL HEALTH CORP		64.31%	-9.0
210	OptiNose Inc.		61.74%	-68.0
211	Genprex Inc.		59.95%	100.0
212	MEI Pharma Inc.		58.82%	-201.0
213	ELI LILLY & Co		57.31%	-1.0
214	Fibrocell Science Inc.		56.46%	8.0
215	Karyopharm Therapeutics Inc.		54.74%	-37.0
216	Zoetis Inc.		52.89%	-6.0
217	Assertio Therapeutics Inc		50.55%	-117.0
218	MELINTA THERAPEUTICS INC. NEW		48.97%	-11.0
219	COLLEGIUM PHARMACEUTICAL INC		48.24%	-71.0
220	CHINOOK THERAPEUTICS INC.		47.23%	-50.0
221	AMARIN CORP PLC\UK		47.02%	64.0
222	TEVA PHARMACEUTICAL INDUSTRIES LTD		46.51%	0.0
223	CELGENE CORP DE		45.55%	-18.0
224	IntelGenx Technologies Corp.		45.29%	-1.0
225	CNBX Pharmaceuticals Inc.		41.55%	-95.0
226	AMICUS THERAPEUTICS INC.		39.14%	-157.0
227	ROCKWELL MEDICAL INC.		38.21%	-139.0
228	OPIANT PHARMACEUTICALS INC.		37.23%	-119.0
229	Amneal Pharmaceuticals Inc.		36.61%	0.0
230	CytomX Therapeutics Inc.		35.88%	-2.0
231	Oncternal Therapeutics Inc.		35.55%	-87.0
232	Ocuphire Pharma Inc.		35.31%	1.0
233	PIERIS PHARMACEUTICALS INC.		35.26%	10.0
234	XOMA Corp		34.87%	-32.0
235	ACTAVIA LIFE SCIENCES INC.		34.46%	0.0
236	International Stem Cell CORP		34.20%	36.0
237	iBio Inc.		33.41%	11.0
238	Syndax Pharmaceuticals Inc		30.20%	-100.0
239	Sonnet BioTherapeutics Holdings Inc.		29.39%	-31.0
240	NovaBay Pharmaceuticals Inc.		28.70%	27.0
241	Lipocine Inc.		28.31%	-53.0
242	AKORN INC		28.02%	-70.0
243	SOLIGENIX INC.		25.85%	-40.0
244	BELLICUM PHARMACEUTICALS INC		22.63%	-40.0
245	ALDER BIOPHARMACEUTICALS INC		22.14%	-92.0
246	TherapeuticsMD Inc.		21.52%	-170.0
247	Aptevo Therapeutics Inc.		18.89%	-179.0
248	BIODELIVERY SCIENCES INTERNATIONAL INC		18.46%	0.0
249	Adamas Pharmaceuticals Inc		12.41%	-12.0
250	Organogenesis Holdings Inc.		11.47%	0.0
251	AILERON THERAPEUTICS INC		10.62%	-198.0
252	Biohaven Pharmaceutical Holding Co Ltd.		8.70%	-102.0
253	Flexion Therapeutics Inc		8.24%	-85.0
254	OCULAR THERAPEUTIX INC		3.13%	20.0
255	Bausch Health Companies Inc.		1.85%	-36.0
256	ONCOSEC MEDICAL Inc		1.53%	0.0
257	Enveric Biosciences Inc.		1.41%	-51.0
258	Pulmatrix Inc.		-2.17%	-7.0
259	Teligent Inc.		-2.67%	-39.0
260	Wave Life Sciences Ltd.		-2.72%	-123.0
261	Qualigen Therapeutics Inc.		-6.82%	-210.0
262	Avalo Therapeutics Inc.		-6.84%	-203.0
263	ChemoCentryx Inc.		-7.19%	-99.0
264	Ainos Inc.		-7.55%	-33.0
265	Paratek Pharmaceuticals Inc.		-11.04%	-49.0
266	Clovis Oncology Inc.		-14.84%	-57.0
267	Evoke Pharma Inc		-17.62%	0.0
268	VACCINEX INC.		-21.80%	0.0
269	Jaguar Health Inc.		-21.88%	-42.0
270	PUMA BIOTECHNOLOGY INC.		-22.55%	24.0
271	Corbus Pharmaceuticals Holdings Inc.		-25.07%	-181.0
272	DYNAVAX TECHNOLOGIES CORP		-28.43%	-222.0
273	SOPHIRIS BIO INC.		-30.75%	-43.0
274	CYTOKINETICS INC		-31.08%	-49.0
275	Vistagen Therapeutics Inc.		-31.32%	40.0
276	VIVUS INC		-32.79%	-19.0
277	CANNAPHARMARX INC.		-35.02%	0.0
278	Neos Therapeutics Inc.		-35.54%	-2.0
279	GALECTIN THERAPEUTICS INC		-36.63%	0.0
280	OMEROS CORP		-39.01%	-146.0
281	INTEGRATED BIOPHARMA INC		-48.45%	-8.0
282	LEAP THERAPEUTICS INC.		-48.82%	-7.0
283	Ayala Pharmaceuticals Inc.		-50.05%	-39.0
284	ImmunoGen Inc.		-51.73%	-13.0
285	Aquestive Therapeutics Inc.		-53.83%	0.0
286	INTERCEPT PHARMACEUTICALS INC.		-55.46%	-7.0
287	LEXICON PHARMACEUTICALS INC.		-55.78%	-33.0
288	Zyla Life Sciences		-56.95%	-2.0
289	PORTOLA PHARMACEUTICALS INC		-57.03%	-109.0
290	Esperion Therapeutics Inc.		-63.01%	-182.0
291	NeuroBo Pharmaceuticals Inc.		-64.94%	5.0
292	Mersana Therapeutics Inc.		-66.20%	-181.0
293	Dermira Inc.		-67.95%	-40.0
294	Societal CDMO Inc.		-68.54%	-48.0
295	Onconova Therapeutics Inc.		-73.76%	34.0
296	Myovant Sciences Ltd.		-78.23%	-232.0
297	Sio Gene Therapies Inc.		-79.18%	-68.0
298	Actinium Pharmaceuticals Inc.		-81.05%	-35.0
299	Fortress Biotech Inc.		-82.35%	0.0
300	Hepion Pharmaceuticals Inc.		-84.04%	-58.0
301	Checkpoint Therapeutics Inc.		-84.55%	-75.0
302	Innovation1 Biotech Inc.		-86.86%	22.0
303	Salarius Pharmaceuticals Inc.		-103.60%	-118.0
304	BIOVIE INC.		-104.81%	-86.0
305	Guardion Health Sciences Inc.		-109.56%	-202.0
306	CorMedix Inc.		-112.13%	1.0
307	First Wave BioPharma Inc.		-113.44%	0.0
308	AVEO PHARMACEUTICALS INC.		-125.53%	-6.0
309	Seres Therapeutics Inc.		-125.62%	-70.0
310	United Cannabis Corp		-127.22%	-137.0
311	SELLAS Life Sciences Group Inc.		-130.48%	-33.0
312	Clearside Biomedical Inc.		-130.58%	-32.0
313	Emmaus Life Sciences Inc.		-133.40%	-81.0
314	Anixa Biosciences Inc		-138.13%	-227.0
315	Viracta Therapeutics Inc.		-148.14%	-75.0
316	ADIAL PHARMACEUTICALS INC.		-161.07%	0.0
317	TG THERAPEUTICS INC.		-184.56%	-67.0
318	PROTEO INC		-189.00%	-8.0
319	Regulus Therapeutics Inc.		-190.50%	-61.0
320	SEELOS THERAPEUTICS INC.		-194.75%	-225.0
321	Axsome Therapeutics Inc.		-196.86%	-74.0
322	MANNKIND CORP		-198.78%	-9.0
323	Lexaria Bioscience Corp.		-202.68%	-251.0
324	Achaogen Inc.		-230.97%	-140.0
325	CARDAX INC.		-239.08%	-36.0
326	NORTHWEST BIOTHERAPEUTICS INC		-240.66%	-18.0
327	CEN BIOTECH INC		-245.75%	-15.0
328	ENDONOVO THERAPEUTICS INC.		-261.92%	-11.0
329	Innovation Pharmaceuticals Inc.		-263.40%	-30.0
330	Optec International Inc.		-274.38%	-138.0
331	Q BioMed Inc.		-283.14%	11.0
332	ZEVRA THERAPEUTICS INC.		-284.80%	-35.0
333	SANGUI BIOTECH INTERNATIONAL INC		-292.51%	-12.0
334	CQENS Technologies Inc.		-304.99%	-31.0
335	NANOMIX Corp		-305.56%	-17.0
336	vTv Therapeutics Inc.		-314.14%	-27.0
337	Rebus Holdings Inc.		-316.29%	0.0
338	RELMADA THERAPEUTICS INC.		-317.74%	-40.0
339	Adhera Therapeutics Inc.		-318.72%	-55.0
340	Avenir Wellness Solutions Inc.		-323.05%	0.0
341	AXIM BIOTECHNOLOGIES INC.		-335.57%	-25.0
342	REGENEREX PHARMA INC.		-342.77%	0.0
343	Oncotelic Therapeutics Inc.		-342.82%	0.0
344	America Great Health		-365.47%	0.0
345	GeoVax Labs Inc.		-374.47%	-14.0
346	BIO-PATH HOLDINGS INC		-375.90%	-211.0
347	ProtoKinetix Inc.		-392.97%	-33.0
348	GlobeStar Therapeutics Corp		-413.03%	-8.0
349	RespireRx Pharmaceuticals Inc.		-416.37%	-14.0
350	REGENERX BIOPHARMACEUTICALS INC		-418.03%	-30.0
351	Regen BioPharma Inc		-428.15%	-21.0
352	BIOXYTRAN INC		-458.82%	0.0
353	ABVC BIOPHARMA INC.		-470.90%	-52.0
354	Skye Bioscience Inc.		-471.97%	-21.0
355	HUMANIGEN INC		-478.40%	0.0
356	Biostax Corp.		-489.37%	-22.0
357	Hoth Therapeutics Inc.		-522.70%	0.0
358	Propanc Biopharma Inc.		-533.82%	-20.0
359	ARTELO BIOSCIENCES INC.		-555.91%	-326.0
360	Rezolute Inc.		-818.03%	-78.0
361	Evofem Biosciences Inc.		-1057.40%	-57.0
362	Wellness Center USA Inc.		-1122.34%	-21.0
363	One World Products Inc.		-4724.47%	0.0
Rank	Company	Seal	Rating Value	Trend