2018 US Pharma

Financial Strength Rankings using Artificial Intelligence

Top rated	85 of 342
Best rating	921 %
Worst rating	-2,146 %
New companies	62
Negative Economic Capital Ratio	99 of 342

MERRIMACK PHARMACEUTICALS INC climbed 263 positions from 264 to 1 due to its excellent Net Income.Clearside Biomedical Inc. lost 223 positions from 57 to 280 due to its bad Research and Development.XYNOMIC PHARMACEUTICALS HOLDINGS INC. entered the 2018 ranking at rank 5, making it the best newcomer.

Revenues	352 B
Assets	956 B
Expenses	324 B
Stockholders Equity	511 B
Unprofitable Companies	296 of 342

Rank	Company	Seal	Rating Value	Trend
1	MERRIMACK PHARMACEUTICALS INC		920.82%	263.0
2	CONCERT PHARMACEUTICALS INC.		381.87%	81.0
3	CORCEPT THERAPEUTICS INC		365.88%	83.0
4	BIOSPECIFICS TECHNOLOGIES CORP		354.30%	-3.0
5	XYNOMIC PHARMACEUTICALS HOLDINGS INC.		342.98%	0.0
6	SPRING PHARMACEUTICAL GROUP INC.		341.36%	-4.0
7	Jazz Pharmaceuticals plc		327.94%	-3.0
8	Sonoma Pharmaceuticals Inc.		312.92%	137.0
9	ENANTA PHARMACEUTICALS INC		305.19%	-6.0
10	ANAPTYSBIO INC		298.14%	0.0
11	MEI Pharma Inc.		297.55%	0.0
12	ABEONA THERAPEUTICS INC.		283.03%	16.0
13	TENAX THERAPEUTICS INC.		280.30%	43.0
14	Intra-Cellular Therapies Inc.		279.86%	35.0
15	ALPINE IMMUNE SCIENCES INC.		279.53%	54.0
16	ABBOTT LABORATORIES		274.36%	-5.0
17	EAGLE PHARMACEUTICALS INC.		274.19%	-11.0
18	ACHILLION PHARMACEUTICALS INC		269.54%	-11.0
19	CATALYST PHARMACEUTICALS INC.		269.11%	19.0
20	Emergent BioSolutions Inc.		269.06%	72.0
21	Catalent Inc.		267.14%	-9.0
22	Blueprint Medicines Corp		266.02%	9.0
23	Cocrystal Pharma Inc.		262.89%	0.0
24	GERON CORP		257.71%	-8.0
25	MARINUS PHARMACEUTICALS INC.		255.24%	153.0
26	ZOGENIX INC.		253.26%	6.0
27	GLYCOMIMETICS INC		251.13%	96.0
28	CHIMERIX INC		249.56%	-15.0
29	PROCYON CORP		248.85%	0.0
30	China Health Industries Holdings Inc.		248.81%	-9.0
31	VERU INC.		246.87%	-22.0
32	Aclaris Therapeutics Inc.		243.69%	-18.0
33	ARTELO BIOSCIENCES INC.		232.75%	245.0
34	Carisma Therapeutics Inc.		230.58%	-29.0
35	MEDICINOVA INC		229.49%	8.0
36	ALNYLAM PHARMACEUTICALS INC.		229.14%	69.0
37	Merck & Co. Inc.		228.55%	-15.0
38	MyoKardia Inc.		228.31%	33.0
39	GT Biopharma Inc.		225.37%	207.0
40	AbbVie Inc.		225.03%	-30.0
41	CAMBREX CORP		224.57%	25.0
42	UNITED THERAPEUTICS Corp		223.47%	-34.0
43	IMMUNE DESIGN CORP.		222.47%	45.0
44	MACROGENICS INC		220.75%	-10.0
45	ALBIREO PHARMA INC.		215.71%	51.0
46	MUSTANG BIO INC.		213.31%	18.0
47	XBiotech Inc.		212.57%	67.0
48	Revance Therapeutics Inc.		211.96%	22.0
49	Molecular Templates Inc.		211.26%	101.0
50	DYNAVAX TECHNOLOGIES CORP		209.60%	109.0
51	Qualigen Therapeutics Inc.		209.49%	204.0
52	Spero Therapeutics Inc.		208.31%	0.0
53	AILERON THERAPEUTICS INC		206.99%	0.0
54	REGENERON PHARMACEUTICALS INC.		206.83%	21.0
55	ENDOCYTE INC		205.88%	-36.0
56	Mirati Therapeutics Inc.		205.60%	144.0
57	Endo International plc		205.39%	1.0
58	Amphastar Pharmaceuticals Inc.		204.90%	-16.0
59	Avalo Therapeutics Inc.		204.80%	0.0
60	Epizyme Inc.		204.44%	-14.0
61	Citius Pharmaceuticals Inc.		203.56%	37.0
62	Cryoport Inc.		201.99%	176.0
63	VBI Vaccines Inc BC		200.61%	0.0
64	Myovant Sciences Ltd.		199.71%	0.0
65	ARDELYX INC.		198.64%	2.0
66	Neoleukin Therapeutics Inc.		197.01%	-48.0
67	Calithera Biosciences Inc.		196.57%	24.0
68	Aptevo Therapeutics Inc.		194.81%	0.0
69	AMICUS THERAPEUTICS INC.		192.79%	-42.0
70	CymaBay Therapeutics Inc.		191.88%	0.0
71	Aeglea BioTherapeutics Inc.		191.84%	-46.0
72	Lexaria Bioscience Corp.		191.78%	182.0
73	Edesa Biotech Inc.		191.41%	-43.0
74	Apellis Pharmaceuticals Inc.		190.58%	0.0
75	Zynerba Pharmaceuticals Inc.		188.76%	41.0
76	TherapeuticsMD Inc.		187.18%	11.0
77	PROTHENA CORP PUBLIC LTD CO		186.90%	4.0
78	ALIMERA SCIENCES INC		185.82%	-5.0
79	SYNLOGIC INC.		185.18%	-44.0
80	Kura Oncology Inc.		182.26%	-1.0
81	KalVista Pharmaceuticals Inc.		181.97%	0.0
82	Moleculin Biotech Inc.		179.77%	-59.0
83	OPKO HEALTH INC.		179.50%	-36.0
84	FIVE PRIME THERAPEUTICS INC.		179.04%	-69.0
85	ARENA PHARMACEUTICALS INC		178.82%	25.0
86	SUPERNUS PHARMACEUTICALS INC.		177.85%	-27.0
87	Anixa Biosciences Inc		177.67%	0.0
88	ROCKWELL MEDICAL INC.		176.34%	-51.0
89	Savara Inc		176.24%	159.0
90	Corbus Pharmaceuticals Holdings Inc.		175.83%	124.0
91	DURECT CORP		175.33%	125.0
92	Xencor Inc		175.05%	-44.0
93	Xenetic Biosciences Inc.		174.84%	0.0
94	JUNIPER PHARMACEUTICALS INC		173.68%	-33.0
95	SEELOS THERAPEUTICS INC.		173.41%	165.0
96	RELIV INTERNATIONAL INC		173.22%	-11.0
97	Corvus Pharmaceuticals Inc.		172.38%	-80.0
98	G1 Therapeutics Inc.		171.87%	0.0
99	ALEXION PHARMACEUTICALS INC.		171.75%	-22.0
100	Assertio Therapeutics Inc		170.43%	-61.0
101	SPECTRUM PHARMACEUTICALS INC		167.38%	28.0
102	CUMBERLAND PHARMACEUTICALS INC		166.30%	-62.0
103	Guardion Health Sciences Inc.		165.48%	187.0
104	Minerva Neurosciences Inc.		165.25%	-39.0
105	Protagonist Therapeutics Inc		165.01%	0.0
106	LIFECORE BIOMEDICAL INC. \DE\		164.92%	-6.0
107	ARROWHEAD PHARMACEUTICALS INC.		164.69%	27.0
108	Esperion Therapeutics Inc.		163.06%	-82.0
109	OPIANT PHARMACEUTICALS INC.		162.44%	161.0
110	Dicerna Pharmaceuticals Inc		162.36%	0.0
111	Mersana Therapeutics Inc.		161.40%	0.0
112	CV Sciences Inc.		160.33%	37.0
113	OTONOMY INC.		160.00%	-53.0
114	LIGAND PHARMACEUTICALS INC		158.65%	-19.0
115	Arbutus Biopharma Corp		157.23%	96.0
116	Altrazeal Life Sciences Inc.		156.10%	103.0
117	BeiGene Ltd.		153.89%	-72.0
118	Allergan plc		152.73%	-28.0
119	Vanda Pharmaceuticals Inc.		150.56%	-13.0
120	VYNE Therapeutics Inc.		149.45%	0.0
121	Aimmune Therapeutics Inc.		147.81%	0.0
122	Tonix Pharmaceuticals Holding Corp.		146.85%	64.0
123	Tempest Therapeutics Inc.		146.51%	-26.0
124	NANOVIRICIDES INC.		146.36%	1.0
125	Pfenex Inc.		145.85%	-89.0
126	VERTEX PHARMACEUTICALS INC MA		145.51%	9.0
127	BIOMARIN PHARMACEUTICAL INC		145.44%	43.0
128	Theravance Biopharma Inc.		145.24%	-99.0
129	Neurotrope Inc.		144.30%	-67.0
130	CNBX Pharmaceuticals Inc.		143.91%	0.0
131	Sarepta Therapeutics Inc.		143.06%	-11.0
132	CHINA PHARMA HOLDINGS INC.		142.66%	0.0
133	NATURES SUNSHINE PRODUCTS INC		142.38%	-44.0
134	OMEROS CORP		142.12%	34.0
135	BIO-PATH HOLDINGS INC		142.03%	3.0
136	Ra Pharmaceuticals Inc.		141.56%	-116.0
137	Wave Life Sciences Ltd.		140.92%	-84.0
138	Syndax Pharmaceuticals Inc		139.40%	-39.0
139	Histogen Inc.		136.45%	9.0
140	DMK PHARMACEUTICALS Corp		134.31%	-4.0
141	ACADIA PHARMACEUTICALS INC		132.36%	-91.0
142	OptiNose Inc.		132.30%	0.0
143	Syros Pharmaceuticals Inc.		131.18%	-71.0
144	Oncternal Therapeutics Inc.		130.49%	-16.0
145	GYRE THERAPEUTICS INC.		130.03%	38.0
146	ARQULE INC		129.95%	-3.0
147	PERRIGO Co plc		127.59%	16.0
148	COLLEGIUM PHARMACEUTICAL INC		124.69%	-47.0
149	Larimar Therapeutics Inc.		124.27%	-105.0
150	Biohaven Pharmaceutical Holding Co Ltd.		123.36%	0.0
151	Nabriva Therapeutics plc		122.07%	-44.0
152	Travere Therapeutics Inc.		118.84%	-40.0
153	ALDER BIOPHARMACEUTICALS INC		117.10%	-120.0
154	EYENOVIA INC.		117.04%	0.0
155	IVERIC bio Inc.		114.81%	0.0
156	Dova Pharmaceuticals Inc.		114.43%	0.0
157	INFINITY PHARMACEUTICALS INC.		113.39%	-46.0
158	AKCEA THERAPEUTICS INC.		111.18%	0.0
159	EXICURE INC.		110.59%	0.0
160	Xenon Pharmaceuticals Inc.		110.47%	-136.0
161	Aravive Inc.		109.80%	-44.0
162	PFIZER INC		106.96%	0.0
163	AGILE THERAPEUTICS INC		105.36%	-81.0
164	ChemoCentryx Inc.		102.99%	20.0
165	AVADEL PHARMACEUTICALS PLC		102.44%	30.0
166	ORAGENICS INC		101.87%	78.0
167	Altimmune Inc.		100.28%	-36.0
168	Flexion Therapeutics Inc		99.63%	-100.0
169	KINETA INC. DE		97.96%	-118.0
170	CHINOOK THERAPEUTICS INC.		97.55%	-33.0
171	ARATANA THERAPEUTICS INC.		96.41%	-45.0
172	AKORN INC		94.33%	-40.0
173	United Cannabis Corp		94.02%	115.0
174	ANI PHARMACEUTICALS INC		92.22%	-56.0
175	F-star Therapeutics Inc.		91.74%	-19.0
176	JOHNSON & JOHNSON		83.02%	0.0
177	ATOSSA THERAPEUTICS INC.		81.20%	0.0
178	Karyopharm Therapeutics Inc.		81.10%	0.0
179	CASSAVA SCIENCES INC		79.77%	-101.0
180	PORTOLA PHARMACEUTICALS INC		79.38%	9.0
181	ORAMED PHARMACEUTICALS INC.		78.22%	-54.0
182	BRISTOL MYERS SQUIBB CO		77.73%	-67.0
183	AGIOS PHARMACEUTICALS INC.		77.50%	-129.0
184	Achaogen Inc.		77.32%	-51.0
185	Salarius Pharmaceuticals Inc.		76.46%	0.0
186	Imunon Inc.		74.72%	0.0
187	Avid Bioservices Inc.		73.74%	-7.0
188	Lipocine Inc.		73.66%	-114.0
189	LANNETT CO INC		72.92%	-35.0
190	Lifevantage Corp		69.90%	-30.0
191	Capstone Therapeutics Corp.		68.03%	16.0
192	Optec International Inc.		67.83%	0.0
193	ROCKET PHARMACEUTICALS INC.		67.62%	-51.0
194	SteadyMed Ltd.		66.77%	9.0
195	Cellectar Biosciences Inc.		65.86%	-140.0
196	CohBar Inc.		64.73%	-116.0
197	IONIS PHARMACEUTICALS INC		63.62%	1.0
198	Orgenesis Inc.		62.70%	-11.0
199	Eterna Therapeutics Inc.		61.63%	-11.0
200	PHIBRO ANIMAL HEALTH CORP		59.83%	-23.0
201	Kintara Therapeutics Inc.		59.61%	0.0
202	XOMA Corp		58.39%	59.0
203	SOLIGENIX INC.		58.26%	-99.0
204	BELLICUM PHARMACEUTICALS INC		57.74%	-80.0
205	CELGENE CORP DE		57.31%	-38.0
206	Enveric Biosciences Inc.		54.99%	0.0
207	MELINTA THERAPEUTICS INC. NEW		52.78%	0.0
208	Sonnet BioTherapeutics Holdings Inc.		52.36%	-27.0
209	Clovis Oncology Inc.		52.35%	27.0
210	Zoetis Inc.		51.75%	-39.0
211	Verastem Inc.		51.52%	0.0
212	ELI LILLY & Co		50.97%	-68.0
213	PROGENICS PHARMACEUTICALS INC		50.91%	0.0
214	Statera Biopharma Inc.		50.50%	-162.0
215	uniQure N.V.		45.96%	-24.0
216	Paratek Pharmaceuticals Inc.		43.05%	-19.0
217	Akebia Therapeutics Inc.		42.07%	-13.0
218	BIOVIE INC.		36.96%	0.0
219	Bausch Health Companies Inc.		36.88%	0.0
220	Teligent Inc.		36.74%	-55.0
221	SCYNEXIS INC		33.48%	-70.0
222	Fibrocell Science Inc.		33.35%	-26.0
223	IntelGenx Technologies Corp.		33.17%	-70.0
224	Matinas BioPharma Holdings Inc.		31.78%	-77.0
225	CYTOKINETICS INC		25.53%	-123.0
226	Checkpoint Therapeutics Inc.		22.99%	-142.0
227	Jaguar Health Inc.		22.06%	46.0
228	CytomX Therapeutics Inc.		21.25%	-55.0
229	Sio Gene Therapies Inc.		21.21%	-116.0
230	SOPHIRIS BIO INC.		19.65%	-69.0
231	Ainos Inc.		18.61%	27.0
232	Emmaus Life Sciences Inc.		18.54%	43.0
233	Ocuphire Pharma Inc.		17.82%	-139.0
234	Viking Therapeutics Inc.		16.74%	-28.0
235	HERON THERAPEUTICS INC. DE		16.64%	28.0
236	Health-Right Discoveries Inc.		15.93%	35.0
237	Adamas Pharmaceuticals Inc		15.84%	-196.0
238	NEKTAR THERAPEUTICS		11.72%	-37.0
239	Seres Therapeutics Inc.		9.44%	-84.0
240	Viracta Therapeutics Inc.		7.65%	-83.0
241	RENOVARO BIOSCIENCES INC.		6.48%	18.0
242	Hepion Pharmaceuticals Inc.		4.97%	0.0
243	PIERIS PHARMACEUTICALS INC.		0.58%	-103.0
244	Ayala Pharmaceuticals Inc.		-0.16%	-122.0
245	Monopar Therapeutics		-0.19%	0.0
246	Societal CDMO Inc.		-0.27%	-88.0
247	Axsome Therapeutics Inc.		-0.70%	-65.0
248	iBio Inc.		-2.55%	-102.0
249	Theriva Biologics Inc.		-4.31%	-8.0
250	TG THERAPEUTICS INC.		-5.08%	-33.0
251	Pulmatrix Inc.		-5.69%	-14.0
252	TESARO Inc.		-9.38%	-133.0
253	Dermira Inc.		-9.43%	-177.0
254	LEXICON PHARMACEUTICALS INC.		-9.61%	0.0
255	LIXTE BIOTECHNOLOGY HOLDINGS INC.		-11.14%	26.0
256	NightHawk Biosciences Inc.		-12.89%	-46.0
257	VIVUS INC		-17.27%	-63.0
258	Regulus Therapeutics Inc.		-18.84%	-65.0
259	TREVENA INC		-20.90%	-83.0
260	Old API Wind-down Ltd.		-21.15%	-70.0
261	Corium International Inc.		-25.94%	-43.0
262	Impax Laboratories LLC		-26.68%	-83.0
263	Actinium Pharmaceuticals Inc.		-26.84%	-91.0
264	CTI BIOPHARMA CORP		-27.51%	-39.0
265	PLx Pharma Winddown Corp.		-27.91%	-90.0
266	HARROW INC.		-33.12%	-53.0
267	NovaBay Pharmaceuticals Inc.		-33.49%	-62.0
268	ARRAY BIOPHARMA INC		-35.38%	-35.0
269	TYME TECHNOLOGIES INC.		-35.50%	0.0
270	ATHERSYS INC NEW		-36.29%	-62.0
271	ImmunoGen Inc.		-41.76%	-37.0
272	International Stem Cell CORP		-43.19%	-131.0
273	INTEGRATED BIOPHARMA INC		-43.24%	-44.0
274	OCULAR THERAPEUTIX INC		-43.46%	-135.0
275	LEAP THERAPEUTICS INC.		-46.32%	0.0
276	Neos Therapeutics Inc.		-50.94%	-37.0
277	Astria Therapeutics Inc.		-59.01%	-111.0
278	SELLAS Life Sciences Group Inc.		-62.15%	-109.0
279	INTERCEPT PHARMACEUTICALS INC.		-69.76%	-87.0
280	Clearside Biomedical Inc.		-74.33%	-223.0
281	MusclePharm Corp		-80.52%	-69.0
282	Rezolute Inc.		-88.12%	-83.0
283	OncoMed Pharmaceuticals Inc		-91.10%	-57.0
284	Adhera Therapeutics Inc.		-91.42%	0.0
285	AMARIN CORP PLC\UK		-92.63%	-61.0
286	Zyla Life Sciences		-97.91%	-58.0
287	KIORA PHARMACEUTICALS INC		-108.25%	-40.0
288	KERYX BIOPHARMACEUTICALS INC		-113.14%	-43.0
289	CARDAX INC.		-114.08%	-22.0
290	AYTU BIOPHARMA INC		-120.23%	-67.0
291	Strongbridge Biopharma plc		-121.93%	0.0
292	EOM Pharmaceutical Holdings Inc.		-134.83%	-60.0
293	Marker Therapeutics Inc.		-139.95%	0.0
294	PUMA BIOTECHNOLOGY INC.		-144.21%	-132.0
295	Bellerophon Therapeutics Inc.		-155.57%	-110.0
296	NeuroBo Pharmaceuticals Inc.		-156.26%	-193.0
297	ZEVRA THERAPEUTICS INC.		-175.23%	-75.0
298	RELMADA THERAPEUTICS INC.		-179.18%	-190.0
299	Innovation Pharmaceuticals Inc.		-183.40%	-68.0
300	NVN Liquidation Inc.		-184.08%	-91.0
301	ABVC BIOPHARMA INC.		-187.41%	-16.0
302	AVEO PHARMACEUTICALS INC.		-191.48%	-62.0
303	CQENS Technologies Inc.		-193.00%	-46.0
304	Evofem Biosciences Inc.		-193.02%	-174.0
305	SIGA TECHNOLOGIES INC		-193.32%	-55.0
306	MABVAX THERAPEUTICS HOLDINGS INC.		-207.61%	-64.0
307	CorMedix Inc.		-209.28%	-133.0
308	NORTHWEST BIOTHERAPEUTICS INC		-214.61%	-56.0
309	vTv Therapeutics Inc.		-234.28%	-107.0
310	PROTEO INC		-240.22%	-59.0
311	Genprex Inc.		-246.55%	0.0
312	CEN BIOTECH INC		-252.51%	-47.0
313	MANNKIND CORP		-253.55%	-78.0
314	ProtoKinetix Inc.		-262.93%	-58.0
315	Vistagen Therapeutics Inc.		-270.14%	-24.0
316	AXIM BIOTECHNOLOGIES INC.		-280.77%	0.0
317	ENDONOVO THERAPEUTICS INC.		-290.14%	0.0
318	NANOMIX Corp		-290.46%	-52.0
319	Phio Pharmaceuticals Corp.		-292.29%	-198.0
320	REGENERX BIOPHARMACEUTICALS INC		-297.28%	-58.0
321	SANGUI BIOTECH INTERNATIONAL INC		-341.42%	0.0
322	Ampio Pharmaceuticals Inc.		-341.56%	-92.0
323	Oncolix Inc.		-361.38%	-31.0
324	Innovation1 Biotech Inc.		-374.26%	0.0
325	Retrieve Medical Holdings Inc.		-385.21%	0.0
326	Cell Source Inc.		-388.60%	0.0
327	Kaya Holdings Inc.		-400.75%	-50.0
328	NEUROPATHIX INC.		-404.66%	-60.0
329	Onconova Therapeutics Inc.		-410.74%	-109.0
330	Regen BioPharma Inc		-414.22%	-41.0
331	GeoVax Labs Inc.		-418.34%	-49.0
332	HypGen Inc		-447.54%	-83.0
333	Skye Bioscience Inc.		-467.00%	-53.0
334	Biostax Corp.		-470.35%	-48.0
335	RespireRx Pharmaceuticals Inc.		-496.65%	-51.0
336	Anthera Pharmaceuticals Inc		-565.77%	-83.0
337	Greater Cannabis Company Inc.		-605.37%	0.0
338	Propanc Biopharma Inc.		-616.63%	-51.0
339	9 METERS BIOPHARMA INC.		-680.41%	-124.0
340	GlobeStar Therapeutics Corp		-818.04%	0.0
341	Wellness Center USA Inc.		-939.26%	0.0
342	Q BioMed Inc.		-2145.68%	-68.0
Rank	Company	Seal	Rating Value	Trend